Median Doses: LD50, ED50 and TD50
ED50: Median effective dose
The dose required to achieve 50% of the desired response in 50% of the population
TD50: Median Toxic dose of 50% for 50%:
The dose required to get 50% of the population reporting this specific toxic effect
LD50: Median lethal dose.
The dose required to achieve 50% mortality from toxicity
EC50: Half maximum effective concentration
The concentration of a drug at which 50% of its maximum response is observed
LC50: Half lethal concentration
The concentration of a drug at which 50% mortality from toxicity is observed
For this sort of really basic stuff, no matter where you look you will find essentially the same information.
I used chapters from “Goodman & Gilman’s The Pharmacological Basis of Therapeutics” 11th ed by Brunton et al, and “Basic & Clinical Pharmacology” 11th ed. By Katzung et al.
I also perused Peck and Hill “Pharmacology for Anaesthesia and Intensive care” as well as the notoriously error-prone “Handbook of Pharmacology and Physiology in Anaesthetic Practice” by Stoelting and Hillier. Neither covered this subject in a depth I found satisfying.
Goodman and Gilman’s remains a canonical text.